Our API Models
ABLANG-2
AbLang-2 is an antibody-specific language model for paired heavy/light chains that reduces...
ABODYBUILDER2
ABodyBuilder2 predicts all-atom 3D structures of paired antibody variable domains (VH/VL)...
ABODYBUILDER3 LANGUAGE
ABodyBuilder3 Language predicts atomic-resolution 3D Fv structures from paired antibody he...
ABODYBUILDER3 PLDDT
ABodyBuilder3 pLDDT predicts all-atom 3D antibody Fv structures from paired heavy (H) and...
ALPHAFOLD2
AlphaFold2 predicts atomic-resolution 3D protein structures from amino acid sequence using...
ANTIFOLD
AntiFold is an antibody-specific inverse folding model that designs sequences conditioned...
BIOLM-ABLEF
BioLM-AbLEF encodes paired antibody Fv heavy/light chain sequences using frozen AbLang emb...
BIOLMSOL
Predict protein and peptide solubility from sequence using the CamSol-like intrinsic solub...
BIOLMTOX-2
BioLMTox-2 is a GPU-accelerated, sequence-only protein toxin classifier fine-tuned from a...
BIOTITE PDB RMSD
Compute the root-mean-square deviation (RMSD) between two protein structures provided as P...
BOLTZ-2
Boltz-2 jointly predicts 3D protein–ligand complex structures and small‑molecule binding a...
CHAI-1
Chai-1 predicts atomic-resolution 3D structures for proteins, antibodies, multimers, nucle...
CLEAN
CLEAN predicts enzyme EC functions directly from amino acid sequence using contrastive lea...
DEEPVISCOSITY
DeepViscosity classifies monoclonal antibodies at 150 mg/mL into low-viscosity (≤20 cP) or...
DIAMOND
DIAMOND provides ultra-fast, sensitive protein sequence alignments at tree-of-life scale,...
DNABERT-2
DNABERT-2 provides GPU-accelerated embeddings and sequence log probabilities for DNA seque...
DNA CHISEL
DNA Chisel computes a configurable set of sequence-level features for linear DNA, includin...
DSM 150M BASE
DSM 150M Base is a 150M-parameter diffusion-trained protein language model that encodes am...
DSM 650M BASE
DSM 650M Base is a 650M-parameter diffusion-based protein language model that unifies repr...
DSM 650M PPI
DSM 650M PPI encodes, scores, and designs protein–protein binders using a 650M-parameter d...
E1 150M
E1 150M is a 150M-parameter retrieval-augmented protein language model for encoding sequen...
E1 300M
E1 300M is a 300M-parameter retrieval-augmented protein encoder that conditions query sequ...
E1 600M
E1 600M is a 600M-parameter retrieval-augmented protein encoder that conditions on up to 5...
ESM1B
Encode protein sequences with the 33-layer ESM-1b Transformer to obtain rich sequence embe...
ESM-1V
ESM-1v scores the functional impact of protein sequence variants using a 650M-parameter tr...
ESM-2 150M
ESM-2 150M is a transformer protein language model that encodes amino acid sequences into...
ESM-2 35M
ESM-2 35M is a compact transformer protein language model for masked language modeling and...
ESM-2 3B
ESM-2 3B is a transformer protein language model trained on UniRef with a masked amino aci...
ESM-2 650M
ESM-2 650M is a transformer protein language model for masked amino acid prediction and se...
ESM-2 8M
ESM-2 8M is a compact transformer protein language model that generates sequence embedding...
ESM2STABP
Predict protein melting temperatures (Tm) and thermophilic vs non-thermophilic class direc...
ESM C 300M
Generate protein sequence embeddings and masked-token predictions using ESM C 300M, a 300M...
ESM C 600M
ESM C 600M is a 600M-parameter transformer protein language model for unsupervised represe...
ESMFOLD
ESMFold predicts atomic-resolution 3D structures of single proteins or small complexes (up...
ESM-IF1
Generate protein sequences from backbone coordinates using the ESM-IF1 inverse folding mod...
EVO 1.5 8K BASE
Evo 1.5 8k Base is a 7B-parameter autoregressive genomic language model trained on ~300B n...
EVO 2 1B BASE
Evo 2 1B Base is a genomic language model for DNA sequence analysis and generation, traine...
EVO V1.5-8K BASE
1.5-B parameter Evo multimodal LM (DNA/RNA) with 8 k context; supports log-prob scoring an...
GLOBAL LABEL MEMBRANE MPNN
Design protein sequences on fixed backbones using a ProteinMPNN variant globally condition...
HYPERMPNN
HyperMPNN designs thermostable protein variants from single-chain 3D structures by retrain...
IGBERT PAIRED
IgBert is an antibody-specific BERT model trained on over two billion unpaired and two mil...
IGT5 PAIRED
IgT5 Paired encodes antibody variable-region heavy–light chain pairs into contextual embed...
IGT5 UNPAIRED
Generate antibody-specific embeddings for unpaired variable region sequences using IgT5, a...
IMMUNEFOLD ANTIBODY
ImmuneFold predicts atomic-level 3D structures of antibodies and nanobodies from amino aci...
IMMUNEFOLD TCR
ImmuneFold TCR predicts atomic-resolution 3D structures of T-cell receptors using a LoRA-f...
LIGANDMPNN
LigandMPNN designs protein sequences and sidechain conformations in explicit atomic contex...
MPNN
ProteinMPNN generative design model. Supports sequence generation from input PDBs.
MSA TRANSFORMER
MSA Transformer encodes protein multiple sequence alignments to produce structure-aware se...
NANOBERT
nanoBERT is a nanobody-specific BERT model trained on 10 million INDI VHH sequences for ma...
NANOBODYBUILDER2
NanoBodyBuilder2 predicts all-atom 3D structures for single-chain nanobody (VHH) heavy-cha...
OMNI-DNA 1B
Omni-DNA 1B is a transformer-based genomic language model that encodes unambiguous DNA seq...
PEPTIDES
Compute a rich set of physicochemical and structural descriptors for peptide and protein s...
PER-RESIDUE LABEL MEMBRANE MPNN
Design protein sequences for membrane protein backbones using a ProteinMPNN variant traine...
PRO4S CLASSIFICATION
Pro4S Classification predicts protein solubility from amino acid sequence and correspondin...
PRO4S REGRESSION
Pro4S Regression predicts quantitative protein solubility (0–1 score) from amino acid sequ...
PROGEN2 BFD90
Generate up to 3 plausible protein sequence continuations from an enzyme-like N-terminal p...
PROGEN2 LARGE
Generate up to three plausible protein sequences by autoregressively extending a user-prov...
PROGEN2 MEDIUM
Generate up to 3 plausible protein sequence continuations from an N-terminal context using...
PROGEN2 OAS
Generate up to 3 antibody VH sequences autoregressively using the OAS-trained ProGen2 vari...
PROSTT5 AA2FOLD
ProstT5 AA2Fold predicts 3Di fold sequences directly from amino acid input using a bilingu...
PROSTT5 FOLD2AA
ProstT5 Fold2AA generates amino acid sequences from protein 3Di structural token strings a...
PROTEINMPNN
Design protein sequences for fixed 3D backbones using ProteinMPNN, a message-passing neura...
SADIE ANTIBODY
SADIE annotates antibody amino acid sequences to assign V/J genes, CDR and framework bound...
SOLUBLE PROTEINMPNN
Design soluble protein sequences for complex and membrane-derived folds from fixed backbon...
SOLUPROT
SoluProt predicts the probability of soluble overexpression of recombinant proteins in *E....
SPURS
SPURS predicts changes in protein thermostability (ΔΔG, kcal/mol) for amino acid substitut...
TCRBUILDER2
TCRBuilder2 predicts 3D T-cell receptor variable-domain structures from paired alpha (A) a...
TCRBUILDER2+
TCRBuilder2+ predicts atomic-level 3D structures of paired T-cell receptors from alpha (A)...
TEMBERTURE CLASSIFIER
TemBERTure is an adapter-finetuned protBERT-BFD model for protein thermostability analysis...
TEMBERTURE REGRESSION
Predict protein melting temperature (Tm, °C) and thermal class from amino acid sequence us...
TEMPRO 3B
TEMPRO 3B predicts nanobody (sdAb/VHH) melting temperature (Tm, °C) directly from amino ac...
TEMPRO 650M
TEMPRO 650M predicts nanobody (VHH/sdAb) melting temperature (Tm) directly from amino acid...
THERMOMPNN
ThermoMPNN predicts ΔΔG for single amino acid substitutions in structured proteins using a...
THERMOMPNN-D
ThermoMPNN-D predicts protein stability changes (ΔΔG, kcal/mol) for single and double poin...
XGBOOST FINETUNE INFERENCE
Run inference against an XGBoost model you previously finetuned on BioLM. Pass the trainin...
XGBOOST FINETUNE TRAINING
Train a custom XGBoost model on your protein or DNA sequences. Submit training data (train...
ZYMCTRL
ZymCTRL is a conditional enzyme language model trained on >36M BRENDA sequences to generat...
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