ESM-IF1

Generate protein sequences from backbone coordinates using the ESM-IF1 inverse folding model. Given a PDB structure, the service samples up to 3 sequences per request for a specified chain, with configurable temperature and optional multi-chain conditioning for complexes. Outputs include designed amino acid sequences and per-sample native sequence recovery, enabling fixed-backbone and interface-focused protein design, as well as rapid in silico exploration of sequence variants compatible with a target 3D conformation.