ESMFold

ESMFold predicts atomic-resolution 3D structures of single proteins or small complexes (up to 4 chains, provided as colon-separated sequences) directly from amino acid sequence without MSAs or templates. The service runs the ESM-2-based folding network on GPU with batch prediction (up to 2 sequences, length ≤ 768 residues each, including chain separators) and returns PDB-formatted coordinates plus mean pLDDT and pTM confidence scores, supporting protein engineering, metagenomic annotation, and structural analysis workflows.