ImmuneFold TCR

ImmuneFold TCR predicts atomic-resolution 3D structures of T-cell receptors using a LoRA-fine-tuned Evoformer trunk on top of ESMFold. The API supports sequence-based TCR complex modeling from paired α/β chains plus peptide–MHC (A, B, P, M), with sequence lengths up to 256 and batched inference up to 32 items. Outputs include PDB coordinates and confidence metrics (per-residue pLDDT, global pLDDT, pTM), enabling structure-guided analysis and downstream, structure-based TCR–epitope binding assessment.