ZymCTRL

ZymCTRL is a conditional enzyme language model trained on >36M BRENDA sequences to generate artificial enzymes conditioned on EC numbers and encode them into sequence embeddings. The API exposes two actions: generation of amino acid sequences up to 1,024 residues from user-specified EC numbers, and encoding of sequences into fixed-length or per-residue embeddings, optionally conditioned on EC. Typical uses include designing candidate enzymes for specific catalytic reactions, exploring sequence space distant from known enzymes, and deriving representations for downstream modeling.